The 374th Strategic Missile Squadron is an inactive United States Air Force unit. It was last assigned to the 308th Strategic Missile Wing, stationed at Little Rock Air Force Base, Arkansas. The squadron was equipped with the LGM-25C Titan II Intercontinental ballistic missile (ICBM), with a mission of nuclear deterrence. The squadron was inactivated as part of the phaseout of the Titan II ICBM on 15 August 1986.