The Manned Orbiting Laboratory (MOL) was part of the United States Air Force (USAF) human spaceflight program in the 1960s. The project was developed from early USAF concepts of crewed space stations as reconnaissance satellites, and was a successor to the canceled Boeing X-20 Dyna-Soar military reconnaissance space plane. Plans for the MOL evolved into a single-use laboratory, for which crews would be launched on 30-day missions, and return to Earth using a Gemini B spacecraft derived from NASA's Gemini spacecraft and launched with the laboratory.

The MOL program was announced to the public on 10 December 1963 as an inhabited platform to demonstrate the utility of putting people in space for military missions; its reconnaissance satellite mission was a secret black project. Seventeen astronauts were selected for the program, including Major Robert H. Lawrence Jr., the first African-American astronaut. The prime contractor for the spacecraft was McDonnell Aircraft Corporation; the laboratory was built by the Douglas Aircraft Company. The Gemini B was externally similar to NASA's Gemini spacecraft, although it underwent several modifications, including the addition of a circular hatch through the heat shield, which allowed passage between the spacecraft and the laboratory. Vandenberg Space Launch Complex 6 (SLC-6) was developed to permit launches into polar orbit.